THE DISTRIBUTION OF CLASS I HLA ANTIGENS IN 1000 NORMAL INDIVIDUALS IN KHORASAN PROVINCE

Authors

  • B NIKBIN From the" Department of Immunology. Faculty of Medicine, Tehran University of Medical Sciences, Tehran
  • H AMINA From the "Department of Immunology, Ghaem Medical Center, Mashad University of Medical Sciences, Mashad
  • H BARADARAN From the "Department of Immunology, Ghaem Medical Center, Mashad University of Medical Sciences, Mashad
  • I DAYHIMI From the" Department of Immunology. Faculty of Medicine, Tehran University of Medical Sciences, Tehran
  • J TAVAKOLI From the "Department of Immunology, Ghaem Medical Center, Mashad University of Medical Sciences, Mashad
  • R FARID From the "Department of Immunology, Ghaem Medical Center, Mashad University of Medical Sciences, Mashad
Abstract:

In this paper, the antigen and gene frequencies of class I HLA antigens were evaluated in 1000 individuals in Khorasan province in northeast Iran, and compared with statistics of other countries. The results and a general discussion are presented.

Upgrade to premium to download articles

Sign up to access the full text

Already have an account?login

similar resources

the distribution of class i hla antigens in 1000 normal individuals in khorasan province

in this paper, the antigen and gene frequencies of class i hla antigens were evaluated in 1000 individuals in khorasan province in northeast iran, and compared with statistics of other countries. the results and a general discussion are presented.

full text

Frequency of Major Histocompatibility Antigens Class I in Mazandaran Province

 Background and purpose: Major histocompatibility antigens are the most polymorphic components of the immune system. The purpose of this study was to determine the frequency of human leukocyte antigens (HLA) in a population in Mazandaran province, Iran. Materials and methods: In a cross sectional study, peripheral blood samples were obtained from 550 people in Immunogenetics Research Center af...

full text

HLA Class I and Class II Genes Distribution of the Sistanis in Iran

Background: The high polymorphism in the human leukocyte antigen (HLA) genes can be used as an identity of individuals to compare with other populations. This extreme polymorphism in the HLA system is accountable for the differences in alleles and haplotypes among ethnic groups, populations, and the inhabitants of many regions. Objective: To define the frequency of HLA alleles and haplotypes am...

full text

Expression of HLA class I antigens in sporadic adenomas and histologically normal mucosa of the colon.

The loss of HLA antigens by neoplastic cells is considered important for tumor growth and metastasis, inasmuch as it may allow tumors to escape immune surveillance. We have observed reduced expression of HLA antigens in sporadic colon cancer and adenomas from familial adenomatous polyposis patients. We now studied the expression of HLA class I antigens in patients with sporadic adenomas, which ...

full text

Distribution of HLA class 1 antigens in normal human tissue and in mammary cancer.

With a monoclonal antibody which reacts with all HLA class 1 antigens it was found that these antigens are not uniformly distributed in all nucleated cells. Rather HLA class 1 antigens are restricted in their distribution to lymphoid cells, endothelial cells of small vessels, and certain epithelia including mammary duct cells. These antigens were not detected on hepatocytes, specialised cells o...

full text

Distribution of human Class I (HLA-A,B,C) histocompatibility antigens in normal and malignant tissues of nonlymphoid origin.

Indirect immunofluorescence and immunoperoxidase staining of surgically removed tissues of nonlymphoid origin with monoclonal antibodies to the heavy and light chain of HLA-A,B,C antigens have shown that they have a more restricted tissue distribution than previously assumed. HLA-A,B,C antigens were not detected in brain cortex, cerebellum, sympathetic ganglia, hypophysis, parathyroid gland, th...

full text

My Resources

Save resource for easier access later

Save to my library Already added to my library

{@ msg_add @}


Journal title

volume 3  issue 1

pages  43- 45

publication date 1989-08

By following a journal you will be notified via email when a new issue of this journal is published.

Keywords

Hosted on Doprax cloud platform doprax.com

copyright © 2015-2023